Cloning and DNA sequence analysis of the cDNA for the precursor of the beta chain of bovine follicle stimulating hormone.
نویسندگان
چکیده
Follicle stimulating hormone (FSH) plays essential roles in the maintenance and development of oocytes and spermatozoa in normal reproductive physiology. FSH possesses two subunits, alpha and beta, the latter being responsible for FSH biological specificity. We have cloned and sequenced the cDNA encoding the FSH beta chain from a bovine anterior pituitary cDNA library. The mature molecule is 109 amino acids long and is preceded by a 20-amino acid putative signal peptide. RNA gel blot analysis of bovine pituitary RNA shows that the mRNA encoding beta chain of FSH is approximately 1.7 kilobases in length.
منابع مشابه
Cloning and expression of Iranian Turkmen-thoroughbred horse follicle stimulating hormone in Pichia pastoris
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ورودعنوان ژورنال:
- Proceedings of the National Academy of Sciences of the United States of America
دوره 83 17 شماره
صفحات -
تاریخ انتشار 1986